Sickle cell anemia

Sickle cell anemia is a genetic blood disorder characterized by abnormal hemoglobin, the protein in red blood cells that carries oxygen throughout the body. In sickle cell anemia, the hemoglobin forms stiff, sickle shaped cells instead of flexible, round shape of normal red blood cells. These sickle shaped cells can get stuck in small blood vessels, leading to pain, organ damage and a variety of complications.

Symptoms: Fatigue, jaundice, delayed growth and development in children.

Diagnosis: CBC, Peripheral Blood Smear Study, Hemoglobin Electrophoresis

Treatment: Antibiotics to prevent infections, blood transfusions, medications to increase hemoglobin production and bone marrow transplantation