Advanced BMT for Systemic & Multiple Systemic Sclerosis
A transformative bone marrow transplant solution for severe autoimmune fibrosis and multi-organ involvement.
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What is Systemic & Multiple Systemic Sclerosis?
Systemic sclerosis, also known as scleroderma, is a rare autoimmune disease that causes excessive collagen buildup, leading to skin tightening and connective tissue damage. It can affect vital organs such as the lungs, heart, kidneys, and digestive system, resulting in symptoms like Raynaud’s phenomenon, breathing difficulties, swallowing problems, and pulmonary hypertension.
The disease may silently damage internal organs before severe symptoms appear. When multiple systems are involved, progression becomes aggressive and can significantly impact quality of life. While standard treatments may slow symptoms, they often fail in severe cases, making early diagnosis and advanced options like Bone Marrow Transplant (BMT) important for eligible patients.
BMT Approach for Severe Systemic Sclerosis
Bone marrow transplant targets the underlying autoimmune process, resetting immune function to slow disease progression, protect organs, and improve long-term outcomes in severe cases.
Comprehensive BMT Treatment Approach
Our comprehensive BMT approach includes careful patient evaluation, advanced transplant protocols, multidisciplinary care, continuous monitoring, and long-term follow-up to ensure safety, effectiveness, and improved outcomes.
Comprehensive BMT treatment begins with detailed patient evaluation and eligibility assessment.
A personalized transplant plan is designed based on disease severity and organ involvement.
Advanced conditioning therapy targets the abnormal immune system.
Autologous stem cells are reinfused to rebuild healthy immune function.
Benefits and Outcomes
Advanced BMT has demonstrated improved long-term survival in patients with severe systemic sclerosis. It helps slow disease progression, improves lung function, reduces skin fibrosis, stabilizes organ involvement, and enhances overall quality of life in eligible patients.
- Improved survival
Advanced BMT has shown better long-term survival in patients with severe systemic sclerosis.
- Enhanced Organ Function
Helps improve lung function and stabilize involvement of vital organs.
- Reduced Skin Fibrosis
Decreases skin thickening and improves flexibility over time.
Risks and Considerations
- Treatment-Related Risks
BMT is an intensive procedure and may carry short-term risks during conditioning and recovery.
- Infection Risk
Temporary immune suppression can increase susceptibility to infections.
- Organ Function Requirements
Careful evaluation is required to ensure organs can tolerate the procedure.
- Patient Eligibility
BMT is recommended only for carefully selected patients with progressive disease.
Eligibility and Recommendations
- Recommended for patients with early, rapidly progressive systemic sclerosis and significant risk of organ involvement.
- Eligibility is determined through detailed clinical evaluation and multidisciplinary specialist assessment.
Why Choose Kannappa for BMT / HSCT in Systemic Sclerosis
Kannappa Memorial Hospital is a specialized Haematology and BMT center, committed to delivering exceptional care and support to all BMT patients.
Our multidisciplinary team includes experienced Hematologists, Rheumatologists, Pathologists, Microbiologists, Psychologists, and a highly skilled Nursing team.
Kannappa Memorial Hospital also offers in-house CD34 selection and enrichment, enhancing outcomes in systemic sclerosis by eliminating autoreactive lymphocytes.
Dr. Margaret Chellaraj
MD DM. Chief of Hematology ( Former HOD of Hematology , Madras Medical College , and Chief Haematologist RGGGH.
Dr. Steve Thomas
MD( CMC , Vellore) DM ( AIIMS ) Consultant Hematologist and BMt Physician
Dr. M. Srikanth
MD MRCP (UK) FRCPath ( UK) CGT( UK )
Senior Consultant Hematologist and CAR-T Cell Therapy Specialist
Dr. Jesu Pandian
MD ( Path ) DNB ( Hematology) BMT Physician
Dr. A.R.Jaswanthini
MD , DNB , Clinical Hematology .
Consultant Hematolgist , Paediatric Hemato Oncologist and BMT Physician .
Dr. Anuraga Srinivasan
MD FNB( CMC), Trannfusion Medicine and Clinical Hematologist
Dr.SP.Ganesan
MBBS DCP , Clinical Pathologist
Dr.Keerthi
MD Microbiology
Mrs. Hemachithra
BMT Coordinator
MrsVijayalakshmi
Customer Support and COO
Healing Stories from Our Patients
Frequently Asked Questions (FAQs)
Bone Marrow Transplant (BMT), or Hematopoietic Stem Cell Transplant (HSCT), is an advanced therapy that resets the immune system, reducing autoimmune attacks and slowing disease progression.
BMT/HSCT is recommended for patients with early, rapidly progressive systemic sclerosis, especially those with multi-organ involvement, after thorough evaluation by specialists.
The treatment can improve survival, enhance lung and organ function, reduce skin fibrosis, stabilize disease progression, and improve overall quality of life.
BMT is an intensive procedure and may involve infection risk, temporary immune suppression, organ-related complications, and is suitable only for carefully selected patients.
The transplant procedure typically takes a few weeks, including conditioning, stem cell infusion, and initial monitoring, with recovery and immune rebuilding continuing for several months.
Yes, we provide continuous monitoring, multidisciplinary follow-up, and specialized care to ensure safety, manage complications, and support long-term recovery.
While it may not cure the disease entirely, BMT/HSCT can significantly slow progression, reduce organ damage, and offer long-term disease control in eligible patients.
You can contact Kannappa Memorial Hospital through our website, phone, or email to schedule an evaluation with our expert hematology and BMT team.